Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 847
Gene Symbol: CAT
CAT
CUI: C0007789
Disease: Cerebral Palsy
Cerebral Palsy
0.040 Biomarker BEFREE On the other hand, tissue antioxidant levels (GSH, GST, and catalase) showed a significant increase in LA-Q-ORMOSIL treated group compared to the CP treated group confirming its high therapeutic efficacy during liver injury. 31819411

2019

Entrez Id: 373156
Gene Symbol: GSTK1
GSTK1
CUI: C0007789
Disease: Cerebral Palsy
Cerebral Palsy
0.010 AlteredExpression BEFREE On the other hand, tissue antioxidant levels (GSH, GST, and catalase) showed a significant increase in LA-Q-ORMOSIL treated group compared to the CP treated group confirming its high therapeutic efficacy during liver injury. 31819411

2019

Entrez Id: 133482
Gene Symbol: SLCO6A1
SLCO6A1
CUI: C0007789
Disease: Cerebral Palsy
Cerebral Palsy
0.010 AlteredExpression BEFREE On the other hand, tissue antioxidant levels (GSH, GST, and catalase) showed a significant increase in LA-Q-ORMOSIL treated group compared to the CP treated group confirming its high therapeutic efficacy during liver injury. 31819411

2019

Entrez Id: 7124
Gene Symbol: TNF
TNF
CUI: C0007789
Disease: Cerebral Palsy
Cerebral Palsy
0.100 Biomarker BEFREE DAS treatment before CP significantly decreased serum urea, creatinine, sodium, potassium, calcium, blood urea nitrogen (BUN), C-reactive protein (CRP), interleukin-6 (IL-6), interleukin-1β (IL-1ß) and tumor necrosis factor-alpha (TNF-α) compared with CP-treated rats. 31779506

2020

Entrez Id: 3569
Gene Symbol: IL6
IL6
CUI: C0007789
Disease: Cerebral Palsy
Cerebral Palsy
0.100 Biomarker BEFREE DAS treatment before CP significantly decreased serum urea, creatinine, sodium, potassium, calcium, blood urea nitrogen (BUN), C-reactive protein (CRP), interleukin-6 (IL-6), interleukin-1β (IL-1ß) and tumor necrosis factor-alpha (TNF-α) compared with CP-treated rats. 31779506

2020

Entrez Id: 3553
Gene Symbol: IL1B
IL1B
CUI: C0007789
Disease: Cerebral Palsy
Cerebral Palsy
0.050 Biomarker BEFREE DAS treatment before CP significantly decreased serum urea, creatinine, sodium, potassium, calcium, blood urea nitrogen (BUN), C-reactive protein (CRP), interleukin-6 (IL-6), interleukin-1β (IL-1ß) and tumor necrosis factor-alpha (TNF-α) compared with CP-treated rats. 31779506

2020

Entrez Id: 1401
Gene Symbol: CRP
CRP
CUI: C0007789
Disease: Cerebral Palsy
Cerebral Palsy
0.020 Biomarker BEFREE DAS treatment before CP significantly decreased serum urea, creatinine, sodium, potassium, calcium, blood urea nitrogen (BUN), C-reactive protein (CRP), interleukin-6 (IL-6), interleukin-1β (IL-1ß) and tumor necrosis factor-alpha (TNF-α) compared with CP-treated rats. 31779506

2020

Entrez Id: 2670
Gene Symbol: GFAP
GFAP
CUI: C0007789
Disease: Cerebral Palsy
Cerebral Palsy
0.020 AlteredExpression BEFREE DAS for 4 consecutive days before CP showed moderate positive immunohistochemically expression of the glial fibrillary acidic protein (GFAP) in the brain and kidney tissues comparable to CP-treated rats. 31779506

2020

Entrez Id: 3552
Gene Symbol: IL1A
IL1A
CUI: C0007789
Disease: Cerebral Palsy
Cerebral Palsy
0.020 Biomarker BEFREE DAS treatment before CP significantly decreased serum urea, creatinine, sodium, potassium, calcium, blood urea nitrogen (BUN), C-reactive protein (CRP), interleukin-6 (IL-6), interleukin-1β (IL-1ß) and tumor necrosis factor-alpha (TNF-α) compared with CP-treated rats. 31779506

2020

Entrez Id: 1789
Gene Symbol: DNMT3B
DNMT3B
CUI: C0007789
Disease: Cerebral Palsy
Cerebral Palsy
0.020 Biomarker BEFREE The comprehensive ICF Core Set for children and young people with CP was in this study used to analyze the areas of functioning discussed, but could also be useful in clinical practice to identify relevant areas of functioning.IMPLICATIONS FOR REHABILITATIONIdentifying areas of functioning facilitate communication among families and multi-disciplinary professionals during rehabilitation team meetings.Important areas of participation are overlooked during intervention planning meetings, which could be improved using ICF-based tools.The comprehensive ICF Core Set for cerebral palsy is a useful framework to identify areas of functioning in Finland. 31755320

2019

Entrez Id: 7124
Gene Symbol: TNF
TNF
CUI: C0007789
Disease: Cerebral Palsy
Cerebral Palsy
0.100 AlteredExpression BEFREE In addition, in CP-treated rats, PGE treatment induced the recovery of white blood cell, neutrophil, and lymphocyte counts, along with mid-range absolute counts, and increased the serum levels of inflammatory cytokines (TNF-α, IFN-γ, IL-2, and IL-12) and immunoglobulins (IgG and IgA). 31752816

2019

Entrez Id: 3558
Gene Symbol: IL2
IL2
CUI: C0007789
Disease: Cerebral Palsy
Cerebral Palsy
0.010 AlteredExpression BEFREE In addition, in CP-treated rats, PGE treatment induced the recovery of white blood cell, neutrophil, and lymphocyte counts, along with mid-range absolute counts, and increased the serum levels of inflammatory cytokines (TNF-α, IFN-γ, IL-2, and IL-12) and immunoglobulins (IgG and IgA). 31752816

2019

Entrez Id: 10533
Gene Symbol: ATG7
ATG7
CUI: C0007789
Disease: Cerebral Palsy
Cerebral Palsy
0.010 AlteredExpression BEFREE The plasma ATG7 level was higher in CP patients compared to the controls (10.58 ± 0.85 vs. 8.18 ± 0.64 pg/mL, <i>p</i> = 0.024). 31749688

2019

Entrez Id: 847
Gene Symbol: CAT
CAT
CUI: C0007789
Disease: Cerebral Palsy
Cerebral Palsy
0.040 Biomarker BEFREE The Relationship between Parent-reported PEDI-CAT Mobility and Gross Motor Function in Children with Cerebral Palsy: Brief Report. 31726912

2020

Entrez Id: 2056
Gene Symbol: EPO
EPO
CUI: C0007789
Disease: Cerebral Palsy
Cerebral Palsy
0.040 GeneticVariation BEFREE Among neonates treated for HIE, the use of erythropoietin (0.36; 0.18-0.74, 2 trials) and whole body hypothermia (0.61; 0.45-0.83; 7 trials) were associated with lower rates of cerebral palsy. 31708771

2019

Entrez Id: 54453
Gene Symbol: RIN2
RIN2
CUI: C0007789
Disease: Cerebral Palsy
Cerebral Palsy
0.010 GeneticVariation BEFREE <i>Methods</i>: Children with CP (n = 12; MACS [Manual Abilities Classification System] levels I-III) and typically developing (TD) children (n = 26) performed an arrow-based version of the Eriksen flanker task where a button press was performed with either the second or third digit of the right hand depending on the arrow's direction. 31679451

2019

Entrez Id: 4082
Gene Symbol: MARCKS
MARCKS
CUI: C0007789
Disease: Cerebral Palsy
Cerebral Palsy
0.010 GeneticVariation BEFREE <i>Methods</i>: Children with CP (n = 12; MACS [Manual Abilities Classification System] levels I-III) and typically developing (TD) children (n = 26) performed an arrow-based version of the Eriksen flanker task where a button press was performed with either the second or third digit of the right hand depending on the arrow's direction. 31679451

2019

Entrez Id: 331
Gene Symbol: XIAP
XIAP
CUI: C0007789
Disease: Cerebral Palsy
Cerebral Palsy
0.010 AlteredExpression BEFREE Our study demonstrates that XIAP overexpressed BMSCs can inhibit the apoptosis of brain nerve cells and the activation of astrocytes, increase AchE activity, and inhibit Ach content, so as to lower the CP caused by cerebral ischemia and hypoxia in rats. 31660045

2019

Entrez Id: 80316
Gene Symbol: PPP1R2C
PPP1R2C
CUI: C0007789
Disease: Cerebral Palsy
Cerebral Palsy
0.080 AlteredExpression BEFREE A total of 182 children, 110 with ABI and 72 with CP and with Gross Motor Function Classification System (GMFCS) levels I-IV, were evaluated retrospectively. 31562873

2020

Entrez Id: 8436
Gene Symbol: CAVIN2
CAVIN2
CUI: C0007789
Disease: Cerebral Palsy
Cerebral Palsy
0.010 AlteredExpression BEFREE Whether the newly modified rhizotomy protocol is applicable to guide single-level approach SDR to treat spastic quadriplegia and diplegia in pediatric patients with cerebral palsy? 31502037

2019

Entrez Id: 116285
Gene Symbol: ACSM1
ACSM1
CUI: C0007789
Disease: Cerebral Palsy
Cerebral Palsy
0.020 GeneticVariation BEFREE The respondents were ten persons aged 22-56 with CP (MACS I-II). 31403825

2019

Entrez Id: 7908
Gene Symbol: EOS
EOS
CUI: C0007789
Disease: Cerebral Palsy
Cerebral Palsy
0.010 Biomarker BEFREE Patients presenting with CP were prospectively selected from our outpatient follow-up consultation at our institutions CP reference centre and underwent conventional supine pelvic and EOS® standing full-leg radiographs the same day for diagnostic and screening reasons. 31391039

2019

Entrez Id: 80316
Gene Symbol: PPP1R2C
PPP1R2C
CUI: C0007789
Disease: Cerebral Palsy
Cerebral Palsy
0.080 GeneticVariation BEFREE <b>Methods</b>: Cohort studies were included if the participants were children with cerebral palsy at Gross Motor Function Classification System (GMFCS) Level I-IV, initial measurement of walking by 13 years of age and follow-up measurement by 30 years of age. 31366265

2019

Entrez Id: 3034
Gene Symbol: HAL
HAL
CUI: C0007789
Disease: Cerebral Palsy
Cerebral Palsy
0.010 Biomarker BEFREE HAL-T can significantly improve CGS, SL, and cadence and may be effective for improving walking ability in adolescents and adults with CP. 31337581

2019

Entrez Id: 6421
Gene Symbol: SFPQ
SFPQ
CUI: C0007789
Disease: Cerebral Palsy
Cerebral Palsy
0.010 AlteredExpression BEFREE A total of 157 patients with nonambulatory CP (Gross Motor Function Classification System IV and V) with a minimum of 2-year follow-up after PSF were identified from a prospective multicenter registry. 31306277

2020